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Sinclair Method Studies

Published on: 11/06/2025

This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.

Why Is It So Difficult to Stop Drinking? The Science Behind Endorphins and Incomplete Treatment

Why Is It So Difficult to Stop Drinking? The Science Behind Endorphins and Incomplete Treatment

Why Is It So Difficult to Stop Drinking? The Science Behind Endorphins and Incomplete TreatmentBruce Rose
Published on: 27/05/2025

Many of us assume that stopping drinking is simply about self-control. But if you've ever tried to cut down—or stop entirely—you'll know it's not that simple. It often feels like you're fighting your own brain. And in many ways, that’s exactly what’s happening.

The Sinclair Method (TSM)
The Biochemistry of Alcohol and Endorphins

The Biochemistry of Alcohol and Endorphins

Published on: 01/05/2024

Detailed examination of how alcohol consumption increases endorphin levels in the brain, affecting mood and behaviour.

Neuroscience
Behavioural Change and Neuroplasticity

Behavioural Change and Neuroplasticity

Published on: 23/04/2024

Discussing the concept of neuroplasticity and its role in behavioural change through The Sinclair Method.

Neuroscience
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